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Psychedelic

Mescaline

also: Peyote · San Pedro · Cactus · Buttons · Mesc

review pending

Content is undergoing medical and legal review. Changes possible.

Natural psychedelic alkaloid from peyote and San Pedro cacti. Long duration, gentle come-up, warm empathogenic qualities. Often described as more grounded than LSD.

Onset

1 h

Peak

4 h

Duration

12 h

Half-life

6 h

Routes

oral

Dosing

Common dose: 200 mg

Strong dose: 500 mg

Risks

  • ·
    Nausea and vomiting common consensus
  • ·
    Very long duration (10-12h) consensus
  • ·
    Bad trip possible consensus
  • ·
    Uncertain potency in plant material consensus
  • ·
    Slow onset can lead to redosing mistakes consensus

Safer Use

  • ·
    Set & setting crucial consensus
  • ·
    Trip sitter recommended consensus
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    Expect nausea in first 2 hours consensus
  • ·
    Don't redose - onset is slow consensus
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    Clear schedule for next day consensus
  • ·
    Ginger for nausea consensus

Drug Checking

Cactus potency varies significantly. Synthetic mescaline HCl allows accurate dosing. - Test with Marquis reagent - Peyote: 0.4% mescaline - San Pedro: 0.3-2% mescaline