Ketamine is a dissociative anesthetic, alcohol a centrally depressant sedative. Both reduce consciousness, swallowing reflex, and motor control.
Clinically relevant consequences:
- K-hole extension — instead of 15–30 minutes it can last 1–2 hours
- Aspiration risk from a reduced swallowing reflex if you vomit
- Circulatory collapse at higher ketamine doses, rare but documented
- Increased forgetfulness and gaps in memory afterwards
Compared to ketamine + GHB/GBL, the respiratory depression is less acute. But the risk of losing control and falling is high — especially in clubs, pools, saunas, or stairwells.
We recommend using them separately (several hours apart). If you do combine them anyway:
- Low ketamine dose (≤ ½ of a usual dose)
- Minimal alcohol
- Never alone
- Not near water, stairs, or sharp edges
- Have a sober person with you